PT-141 10mg – 3ml Vial

(Bremelanotide Research Peptide)

Product Overview

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analogue derived from melanotan II and structurally related to alpha-melanocyte stimulating hormone (α-MSH). It is utilised in laboratory research to investigate melanocortin receptor-mediated signalling mechanisms.

In controlled in-vitro and pre-clinical research systems, PT-141 is commonly studied for:

• Melanocortin-3 receptor (MC3R) binding dynamics

• Melanocortin-4 receptor (MC4R) interaction models

• GPCR-mediated intracellular signalling pathways

• cAMP-associated signal transduction mechanisms

• Structure–activity relationships within melanocortin analogues

Its cyclic peptide structure enhances receptor affinity and structural stability in experimental models.

Supplied in lyophilised form to preserve peptide integrity and analytical stability prior to reconstitution.

Key Features

• Synthetic cyclic melanocortin receptor agonist

• Structurally related to α-MSH analogues

• Studied in MC3R and MC4R receptor research

• Investigated in GPCR and cAMP signalling models

• ≥99% purity (HPLC verified)

• Lyophilised solid for enhanced stability

• 10mg per sterile 3ml glass vial

Product Specifications

• Product Name: PT-141

• Synonyms: Bremelanotide

• Molecular Class: Synthetic cyclic heptapeptide analogue

• Amino Acid Sequence (3-Letter Code):
  Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH₂
  (Cyclic structure; Nle = Norleucine)

• Molecular Formula: C50H68N14O10

• Molecular Weight: ~1025 g/mol

• CAS Number: 189691-06-3

• Purity: ≥99% (HPLC)

• Appearance: White to off-white lyophilised powder

• Net Content: 10mg

• Vial Size: 3ml sterile glass vial

• Storage Form: Lyophilised peptide

• Intended Use: Laboratory research only

Handling & Storage Guidelines

Unreconstituted (Lyophilised) Storage:
Store at −20°C for long-term preservation. Short-term storage at 2–8°C is acceptable if intended for use within 1–3 months.

Reconstituted Storage:
After reconstitution, store at 2–8°C and use within 3–6 weeks. Stability may vary depending on solvent selection and laboratory handling conditions.

Avoid repeated freeze–thaw cycles. Protect from excessive agitation, heat, and direct light exposure.

Manufacturing & Quality

PT-141 is manufactured using precision solid-phase peptide synthesis (SPPS) under GMP-aligned laboratory standards.

Each batch undergoes:

• High Performance Liquid Chromatography (HPLC) purity verification

• Mass spectrometry identity confirmation

• Cyclic structure validation

• Analytical quality control prior to release

• Batch traceability and documentation procedures

Products are released only after meeting strict internal quality specifications.

Legal & Safety Notice

This product is supplied strictly for laboratory research purposes only.

Not for human consumption.
Not for therapeutic, diagnostic, or veterinary use.
Not a licensed medicinal product in the United Kingdom.

The purchaser is responsible for ensuring full compliance with all applicable UK laws and regulations relating to research chemicals.