MOTS-c 10mg – 3ml Vial

Product Overview

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within mitochondrial DNA. It is classified as a mitochondrial-derived peptide (MDP) and is studied in experimental models for its role in metabolic regulation and cellular stress response signalling.

In controlled in-vitro and pre-clinical research systems, MOTS-c is commonly utilised to investigate:

• AMPK-associated metabolic pathway modulation

• Cellular energy homeostasis signalling

• Glucose uptake pathway research

• Mitochondrial-to-nuclear communication mechanisms

• Metabolic stress adaptation models

Due to its mitochondrial origin, MOTS-c is frequently selected for laboratory research involving bioenergetics and intracellular signalling regulation.

Supplied in lyophilised form to preserve peptide stability and analytical integrity prior to reconstitution.

Key Features

• Synthetic mitochondrial-derived peptide (MDP)

• Studied in AMPK and metabolic pathway research

• Investigated in cellular energy regulation models

• Associated with mitochondrial signalling mechanisms

• ≥98–99% purity (HPLC verified)

• Lyophilised solid for enhanced stability

• 10mg per sterile 3ml glass vial

Product Specifications

• Product Name: MOTS-c

• Synonyms: Mitochondrial Open Reading Frame of the 12S rRNA-c

• Molecular Class: Mitochondrial-derived peptide

• Amino Acid Sequence (3-Letter Code):
  Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

• Molecular Formula: C101H152N28O22

• Molecular Weight: ~2174 g/mol

• CAS Number: 1627580-64-6

• Purity: ≥98–99% (HPLC)

• Appearance: White to off-white lyophilised powder

• Net Content: 10mg

• Vial Size: 3ml sterile glass vial

• Storage Form: Lyophilised peptide

• Intended Use: Laboratory research only

Handling & Storage Guidelines

Unreconstituted (Lyophilised) Storage:
Store at −20°C for long-term preservation. Short-term storage at 2–8°C is acceptable if intended for use within 1–3 months.

Reconstituted Storage:
After reconstitution, store at 2–8°C and use within 3–6 weeks. Stability may vary depending on solvent selection and handling conditions.

Avoid repeated freeze–thaw cycles. Protect from excessive agitation, heat, and direct light exposure.

Manufacturing & Quality

MOTS-c is manufactured using precision solid-phase peptide synthesis (SPPS) under GMP-aligned laboratory standards.

Each batch undergoes:

• High Performance Liquid Chromatography (HPLC) purity verification

• Mass spectrometry identity confirmation

• Analytical quality control prior to release

• Batch traceability and documentation procedures

Products are released only after meeting strict internal quality specifications.

Legal & Safety Notice

This product is supplied strictly for laboratory research purposes only.

Not for human consumption.
Not for therapeutic, diagnostic, or veterinary use.
Not a licensed medicinal product in the United Kingdom.

The purchaser is responsible for ensuring full compliance with all applicable UK laws and regulations relating to research chemicals.