HGH Fragment 176–191 5mg – 3ml Vial

Product Overview

HGH Fragment 176–191 corresponds to the C-terminal region of human growth hormone and represents residues 176 through 191 of the full-length 191-amino-acid hGH molecule. This fragment has been structurally isolated for laboratory investigation into metabolic signalling independent of the broader systemic activity associated with intact growth hormone.

In controlled in-vitro and pre-clinical research models, HGH Frag 176–191 is utilised to investigate:

• Adipocyte receptor signalling mechanisms

• Lipolytic pathway modulation

• AMPK-associated metabolic signalling

• Fat oxidation pathway research

• Structure–activity relationships within the GH molecule

Unlike full-length hGH, this fragment does not activate the complete GH receptor cascade, making it suitable for focused mechanistic research into lipid metabolism-associated pathways.

Supplied in lyophilised form to preserve peptide stability and analytical integrity prior to reconstitution.

Key Features

• Synthetic human growth hormone fragment (176–191)

• Studied in lipid metabolism and adipocyte signalling research

• Investigated in AMPK pathway modulation models

• Does not replicate full-length GH receptor activity

• ≥99% purity (HPLC verified)

• Lyophilised solid for enhanced stability

• 5mg per sterile 3ml glass vial

Product Specifications

• Product Name: HGH Fragment 176–191

• Synonyms: hGH Frag 176–191; Growth Hormone Fragment 176–191

• Molecular Class: Synthetic peptide fragment

• Amino Acid Sequence (3-Letter Code):
  Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

• Molecular Formula: C78H123N23O23S2

• Molecular Weight: ~1815.1 g/mol

• CAS Number: 66004-57-7

• Purity: ≥99% (HPLC)

• Appearance: White to off-white lyophilised powder

• Net Content: 5mg

• Vial Size: 3ml sterile glass vial

• Storage Form: Lyophilised peptide

• Intended Use: Laboratory research only

Handling & Storage Guidelines

Unreconstituted (Lyophilised) Storage:
Store at −20°C for long-term preservation. Short-term storage at 2–8°C is acceptable if intended for use within 1–3 months.

Reconstituted Storage:
After reconstitution, store at 2–8°C and use within 3–6 weeks. Stability may vary depending on solvent selection and handling conditions.

Avoid repeated freeze–thaw cycles. Protect from excessive agitation, heat, and direct light exposure.

Manufacturing & Quality

HGH Fragment 176–191 is manufactured using precision solid-phase peptide synthesis (SPPS) under GMP-aligned laboratory standards.

Each batch undergoes:

• High Performance Liquid Chromatography (HPLC) purity verification

• Mass spectrometry identity confirmation

• Analytical quality control prior to release

• Batch traceability and documentation procedures

Products are released only after meeting strict internal quality specifications.

Legal & Safety Notice

This product is supplied strictly for laboratory research purposes only.

Not for human consumption.
Not for therapeutic, diagnostic, or veterinary use.
Not a licensed medicinal product in the United Kingdom.

The purchaser is responsible for ensuring full compliance with all applicable UK laws and regulations relating to research chemicals.