CJC-1295 (No DAC) 5mg – 3ml Vial

Product Overview

CJC-1295 (No DAC), also referred to as Modified GRF (1–29), is a synthetic analogue of growth hormone releasing hormone (GHRH). Unlike the DAC-modified version, this variant does not contain a Drug Affinity Complex, resulting in shorter receptor interaction kinetics in laboratory models.

In vitro and pre-clinical research commonly investigates CJC-1295 (No DAC) for:

• GHRH receptor binding dynamics

• cAMP-mediated intracellular signalling pathways

• Pituitary growth hormone axis modelling

• Pulsatile hormone release mechanisms

• Endocrine feedback pathway analysis

Due to its structural modifications relative to native GHRH (1–29), it demonstrates enhanced receptor affinity and stability in controlled research systems.

Supplied in lyophilised form to preserve structural integrity and analytical purity prior to reconstitution.

Key Features

• Synthetic GHRH analogue (Modified GRF 1–29)

• No Drug Affinity Complex (No DAC) modification

• Studied in GH axis receptor research

• Investigated in cAMP signalling pathway models

• ≥99% purity (HPLC verified)

• Lyophilised solid for enhanced stability

• 5mg per sterile 3ml glass vial

Product Specifications

• Product Name: CJC-1295 (No DAC)

• Synonyms: Modified GRF (1–29); tetrasubstituted GHRH analogue

• Molecular Class: Synthetic GHRH analogue

• Amino Acid Sequence (3-Letter Code):
  Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂

• Molecular Formula: C152H252N44O42

• Molecular Weight: ~3367 g/mol

• CAS Number: 863288-34-0

• Purity: ≥99% (HPLC)

• Appearance: White to off-white lyophilised powder

• Net Content: 5mg

• Vial Size: 3ml sterile glass vial

• Storage Form: Lyophilised peptide

• Intended Use: Laboratory research only

Handling & Storage Guidelines

Unreconstituted (Lyophilised) Storage:
Store at −20°C for long-term preservation. Short-term storage at 2–8°C is acceptable if intended for use within 1–3 months.

Reconstituted Storage:
After reconstitution, store at 2–8°C and use within 3–6 weeks. Stability may vary depending on solvent selection and handling conditions.

Avoid repeated freeze–thaw cycles. Protect from excessive agitation, heat, and direct light exposure.

Manufacturing & Quality

CJC-1295 (No DAC) is manufactured using precision solid-phase peptide synthesis (SPPS) under GMP-aligned laboratory standards.

Each batch undergoes:

• High Performance Liquid Chromatography (HPLC) purity verification

• Mass spectrometry identity confirmation

• Analytical quality control prior to release

• Batch traceability and documentation procedures

Products are released only after meeting strict internal quality specifications.

Legal & Safety Notice

This product is supplied strictly for laboratory research purposes only.

Not for human consumption.
Not for therapeutic, diagnostic, or veterinary use.
Not a licensed medicinal product in the United Kingdom.

The purchaser is responsible for ensuring full compliance with all applicable UK laws and regulations relating to research chemicals.